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中华老年骨科与康复电子杂志 ›› 2021, Vol. 07 ›› Issue (03) : 170 -175. doi: 10.3877/cma.j.issn.2096-0263.2021.03.008

康复医学

加速康复外科在人工股骨头置换术治疗老年股骨粗隆间骨折中的应用研究
董佩龙1, 唐晓波1, 王健1, 李志云1, 谢淑君1,()   
  1. 1. 224700 盐城,南通大学附属建湖医院骨科
  • 收稿日期:2020-06-24 出版日期:2021-06-05
  • 通信作者: 谢淑君
  • 基金资助:
    2018年度江苏省第五期"333工程"科研项目资助计划(BRA2018250); 盐城市医学科技发展计划资助项目(YK2017080)

Clinical study of enhanced recovery after surgery in the treatment of intertrochanteric femoral fracture with artificial femoral head replacement in elderly patients

Peilong Dong1, Xiaobo Tang1, Jian Wang1, Zhiyun Li1, Shujun Xie1,()   

  1. 1. Department of Orthopedics, Affiliated Jianhu Hospital of Nantong University, Yancheng 224700, China
  • Received:2020-06-24 Published:2021-06-05
  • Corresponding author: Shujun Xie
引用本文:

董佩龙, 唐晓波, 王健, 李志云, 谢淑君. 加速康复外科在人工股骨头置换术治疗老年股骨粗隆间骨折中的应用研究[J]. 中华老年骨科与康复电子杂志, 2021, 07(03): 170-175.

Peilong Dong, Xiaobo Tang, Jian Wang, Zhiyun Li, Shujun Xie. Clinical study of enhanced recovery after surgery in the treatment of intertrochanteric femoral fracture with artificial femoral head replacement in elderly patients[J]. Chinese Journal of Geriatric Orthopaedics and Rehabilitation(Electronic Edition), 2021, 07(03): 170-175.

目的

通过临床随机对照研究,探讨加速康复外科(ERAS)在人工股骨头置换术治疗老年股骨粗隆间骨折中的应用效果。

方法

前瞻性收集2016年02月至2018年02月南通大学附属建湖医院骨科收治的52例符合选择标准的拟定行人工股骨头置换术的老年股骨粗隆间骨折患者。其中26例采用ERAS围手术期方案(试验组),男性12例,女性14例,平均年龄(79.7±3.1)岁,26例采用传统围手术期方案(对照组),男性13例,女性13例,平均年龄(78.8±2.6)岁。比较两组术后2 h血红蛋白及输血比例、术后住院时间(LOS)、术后并发症、术后24 h、1个月、3个月、12个月疼痛视觉模拟评分(VAS)、Harris评分。

结果

术后患者均获随访,随访时间12~24个月,平均(18±3)个月。试验组术后24 h血红蛋白[(110.4±13.7)g/L]高于对照组[(100.1±9.0)g/L],试验组术后LOS[(3.6±0.8)d]短于对照组[(4.6±0.8)d],差异均有统计学意义(t=3.204,P=0.002;t=3.749,P=0.001),试验组输血比例及术后并发症发生率低于对照组,差异有统计学意义。试验组和对照组术前、术后24 h、1个月、3个月、12个月VAS评分及Harris评分进行重复测量设计的方差分析显示试验组和对照组组间差异有统计学意义,组别与时间点间存在交互作用,各时间点除第一时间点和第五时间点外两组差异均有统计学意义,试验组在各时间点间差异均有统计学意义。

结论

ERAS理念干预下,人工股骨头置换术治疗老年股骨粗隆间骨折术后失血少、术后住院时间短、并发症发生率低、术后短期疼痛轻,康复快,利于髋关节功能的早期恢复。

Objective

To investigate the effect of enhanced recovery after surgery (ERAS) in the treatment of intertrochanteric femoral fracture with artificial femoral head replacement in elderly patients.

Methods

From Feburary 2016 to Feburary 2018, 52 patients who underwent the treatment of artificial femoral head replacement with intertrochanteric femoral fracture in elderly patients were randomly divided into two groups: ERAS group (experimental group, n=26, including 12 males and 14 female, with a median age of 79.7±3.1 years) and routine group (control group, n=26, including 13 males and 13 female, with a median age of 78.8±2.6 years). Follow-up assessment included postoperative hemoglobin at 24 hours after operation, blood transfusion ratio, postoperative length of stay (LOS), postoperative complications, VAS score and Harris score at 24 hours, 1 month, 3 months and 12 months after operation.

Results

All the 52 patients were followed up for 12-24 months (18±3 months on average). Postoperative hemoglobin at 24 hours after operation in experimental group [(110.4±13.7) g/L] was significantly higher than that in control group [(100.1±9.0) g/L]. The postoperative LOS in the experimental group [(3.6±0.8) d] was significantly shorter than that in the control group [(4.6±0.8) d]. There were significant differences between the two groups (t=3.204, P=0.002, t=3.749, P=0.001). The blood transfusion ratio and the incidence of complications in the experimental group were significantly lower than those in the control group. There were significant differences between the two groups. The VAS score and Harris score of the experimental group and the control group before and after 24 h, 1 month, 3 months, 12 months of repeated measurement design showed that there were significant differences between the experimental group and the control group. There was interaction between the two groups at different time points. Except for the first time point and the fifth time point, the difference between the two groups was statistically significant. There were statistically significant differences in the experimental group at each time point.

Conclusion

The application of ERAS in the treatment of intertrochanteric femoral fracture with artificial femoral head replacement in elderly patients can reduce blood loss and the incidence of complications, shorten hospital stay, cause less short-term pain after operation, achieve faster recovery. It is beneficial to the early recovery of hip joint function.

表1 两组老年股骨粗隆间骨折患者术前临床资料比较
表2 两组老年股骨粗隆间骨折术后部分随访指标及并发症比较
表3 两组老年股骨粗隆间骨折患者术前及术后不同时间点VAS评分的比较(分,±s
表4 两组老年股骨粗隆间骨折患者术前及术后不同时间点髋关节Harris评分的比较(分,±s
图1~6 女性,81岁,左侧股骨粗隆间骨折(Evans-Jensen分型为Ⅳ型),行左侧人工股骨头置换术,术中使用克氏针张力带重建股骨大粗隆。图1~2术前骨盆正位+左侧髋关节侧位片示:左侧股骨粗隆间骨质中断,大小粗隆移位明显;图3~4术后骨盆正位+左侧髋关节侧位片示:髋关节假体在位,大粗隆复位固定良好;图5~6术后3个月骨盆正位+左侧髋关节侧位片示:髋关节假体在位,大粗隆复位固定良好,大粗隆骨折愈合
1
Bouyer B, Leroy F, Rudant J, et al. Burden of fractures in France:incidence and severity by age,gender,and site in 2016 [J]. Int Orthop, 2020: [Epub ahead of print]
2
Ristić B, Ristić DI, Milicić B, et al. Factors which influence postoperative mortality after hip fracture [J]. Vojnosanit Pregl, 2006, 63(1): 49-53.
3
Pui CM, Bostrom MP, Westrich GH, et al. Increased complication rate following conversion total hip arthroplasty after cephalomedullary fixation for intertrochanteric hip fractures: a multi-center study [J]. J Arthroplasty, 2013, 28(8 Suppl): 45-47.
4
董佩龙,唐晓波,王健,等. 股骨头置换术治疗老年股骨粗隆间骨折中克氏针的应用研究[J/CD]. 中华关节外科杂志:电子版,2017,11(1):91-95.
5
Li C, Xie B, Chen S, et a1. The effect of local bone density on mechanical failure after internal fixation of pertrochanteric fractures [J]. Arch Orthop Trauma Surg, 2016, 136(2): 223-232.
6
Gocer H, Coskun S, Karaismailoglu N. Comparison of treatment of unstable intertrochanteric fracture with different arthroplasty met hods [J]. Niger Med J, 2016, 57(2):81-85.
7
Stowers MD, Manuopangai L, Hill AG, et al. Enhanced recovery after surgery in elective hip and knee arthroplasty reduces length of hospital stay [J]. ANZ J Surg, 2016, 86(6): 475-479.
8
中国加速康复外科专家组. 中国加速康复外科围手术期管理专家共识(2016) [J]. 中华外科杂志,2016,54(6):413-418.
9
Siwach RC, Rohilla R, Singh R, et al. Radiological and functional outcome in unstable, osteoporotic trochanteric fractures stabilized with dynamic helical hip system [J]. Strategies Trauma Limb Reconstr, 2013, 8(2): 117-122.

URL    
10
Namdari S, Rabinovich R, Scolaro J, et al. Absorbable and non-absorbable cement augmentation in fixation of intertrochanteric femur fractures: systematic review of the literature [J]. Arch Orthop Trauma Surg, 2013, 133(4): 487-494.
11
YooJI, HaYC, LimJY, et al. Early rehabilitation in elderly after arthroplasty versus internal fixation for unstable intertrochanteric fractures of femur:systematic review and meta-analysis [J]. J Korean Med Sci, 2017, 32(5): 858-867.
12
Kehlet H. ERAS implementation-time to move forward[J]. Ann Surg, 2018, 267(6): 998-999.
13
Kehlet H. Fast-track surgery-an update on physiological care principles to enhance recovery [J]. Langenbecks Arch Surg, 2011, 396(5): 585-590.

URL    
14
Stambough JB, Nunley RM, Curry MC, et al. Rapid recovery protocols for primary total hip arthroplasty can safely reduce length of stay without increasing readmissions [J]. J Arthroplasty, 2015, 30(4): 521-526.
15
蔡宇,周华军,程文俊,等. 加速康复外科联合标准化康复路径在全髋关节置换术治疗老年股骨颈骨折患者中的应用[J]. 中华创伤骨科杂志,2016,18(8):673-678.
16
Zhao-YuC, YanG, WeiC, et al. Reduced blood loss after intra-articular tranexamic acid injection during total knee arthroplasty: a meta-analysis of the literature [J]. Knee Surg Sports Traumatol Arthrosc, 2014, 22(12): 3181-3190.
17
Xie J, Hu Q, Huang Q, et al. Comparison of intravenous versus topical tranexamic acid in primary total hip and knee arthroplasty: An updated meta-analysis [J]. Thromb Res, 2017, 153: 28-36.
18
Peng Zhang, Jifeng Li, Xiao Wang. Combined versus single application of tranexamic acid in total knee and hip arthroplasty: A meta-analysis of randomized controlled trials [J]. Int J Surg, 2017, 43: 171-180.
19
Myles P, Bellomo R, Corcoran T, et al. Restrictive versus Liberal fluid therapy in major abdominal surgery (RELIEF): rationale and design for a multicentre randomised trial [J]. BMJ Open, 2017, 7(3): e015358.
20
Pang O, Liu H, Chen B, et al. Restrictive and Liberal fluid administration in major abdominal surgery [J]. SaudiMedI, 2017, 38(21): 123-131.
21
Ljungqvist O. Modulating postoperative insulin resistance by preoperative carbohydrate loading[J]. Best Pract Res Clin Anaesthesiol, 2009, 23(4):401-409.
22
Mathiesen O, Dahl B, Thomsen BA, et al. A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery [J]. Eur Spine J, 2013, 22(9): 2089-2096.
23
Bruhn J, Gj S, Van Geffen GJ. Clinical application of perioperative multimodal analgesia [J]. Curr Opin Support Palliat Care, 2017, 11(2): 106-111.
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