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中华老年骨科与康复电子杂志 ›› 2024, Vol. 10 ›› Issue (01) : 51 -56. doi: 10.3877/cma.j.issn.2096-0263.2024.01.009

综述

术后房颤对老年髋部骨折患者预后影响的研究进展
张煜彭1, 李浩南1, 付焱1, 冯继伟1, 刘凯2, 张文凯2,()   
  1. 1. 030001 太原,山西医科大学
    2. 030001 太原,山西医科大学第二医院重症医学科
  • 收稿日期:2023-01-27 出版日期:2024-02-05
  • 通信作者: 张文凯
  • 基金资助:
    山西省科技厅自然科学研究面上项目(202203021221278)

Advances in research of postoperative atrial fibrillation on the prognosis of elderly patients with hip fracture

Yupeng Zhang1, Haonan Li1, Yan Fu1, Jiwei Feng1, Kai Liu2, Wenkai Zhang2,()   

  1. 1. Shanxi Medical University, Taiyuan 030001, China
    2. Department of Intensive Care Unit, Second Hospital of Shanxi Medical University, Taiyuan 030001, China
  • Received:2023-01-27 Published:2024-02-05
  • Corresponding author: Wenkai Zhang
引用本文:

张煜彭, 李浩南, 付焱, 冯继伟, 刘凯, 张文凯. 术后房颤对老年髋部骨折患者预后影响的研究进展[J]. 中华老年骨科与康复电子杂志, 2024, 10(01): 51-56.

Yupeng Zhang, Haonan Li, Yan Fu, Jiwei Feng, Kai Liu, Wenkai Zhang. Advances in research of postoperative atrial fibrillation on the prognosis of elderly patients with hip fracture[J]. Chinese Journal of Geriatric Orthopaedics and Rehabilitation(Electronic Edition), 2024, 10(01): 51-56.

术后心房颤动(POAF)是一种严重的外科手术并发症,也是最常见的围术期心律失常,在全球范围内,髋部骨折都是老年人致残的十大原因之一。鉴于髋部骨折发生术后房颤后对患者死亡率的影响逐渐显现,越来越多的研究集中于探究其发病率及对患者结局的影响。本文通过对术后房颤对老年髋部骨折患者预后影响的研究进行分析,总结其可能发生机制的研究进展,挖掘防治及预测其发生的可能性,可指导临床评估、管理和有针对性的干预。

Postoperative atrial fibrillation (POAF) is a serious surgical complication and the most common perioperative arrhythmia. Globally, hip fracture is one of the top ten causes of disability in the elderly. In view of the gradual impact of postoperative atrial fibrillation on the mortality of patients with hip fracture, more and more studies have focused on the incidence of hip fracture and its impact on the outcome of patients. Through the analysis of the effect of postoperative atrial fibrillation on the prognosis of elderly patients with hip fracture, this paper summarizes the research progress of its possible mechanism, excavates the possibility of prevention and treatment and predicts the possibility of its occurrence, which can guide clinical evaluation, management and targeted intervention.

1
Cauley JA, Chalhoub D, Kassem AM, et al. Geographic and ethnic disparities in osteoporotic fractures [J]. Nat Rev Endocrinol, 2014, 10(6): 338-351.
2
Benjamin EJ, Wolf PA, D'Agostino RB, et al. Impact of atrial fibrillation on the risk of death: the Framingham Heart Study [J]. Circulation, 1998, 98(10): 946-952.
3
Bhandari M, Swiontkowski M. Management of acute hip fracture [J]. N Engl J Med, 2017, 377(21): 2053-2062.
4
Beaupre LA, Jones CA, Saunders LD, et al. Best practices for elderly hip fracture patients. A systematic overview of the evidence [J]. J Gen Intern Med, 2005, 20(11): 1019-1025.
5
Wilkins K. Health care Consequences of falls for seniors [J]. Health Rep, 1999, 10(4): 47-55(ENG); 47-57(FRE).
6
Schnell S, Friedman SM, Mendelson DA, et al. The 1-year mortality of patients treated in a hip fracture program for elders [J]. Geriatr Orthop Surg Rehabil, 2010, 1(1): 6-14.
7
Roberts SE, Goldacre MJ. Time trends and demography of mortality after fractured neck of femur in an English population, 1968-98: database study [J]. BMJ, 2003, 327(7418): 771-775.
8
Melton LJ3, Gabriel SE, Crowson CS, et al. Cost-equivalence of different osteoporotic fractures [J]. Osteoporos Int, 2003, 14(5): 383-388.
9
Goldacre MJ, Roberts SE, Yeates D. Mortality after admission to hospital with fractured neck of femur: database study [J]. BMJ, 2002, 325(7369): 868-869.
10
Kannus P, Niemi S, Parkkari J, et al. Hip fractures in Finland between 1970 and 1997 and predictions for the future [J]. Lancet, 1999, 353(9155): 802-805.
11
Roche JJW, Wenn RT, Sahota O, et al. Effect of comorbidities and postoperative complications on mortality after hip fracture in elderly People: prospective observational cohort study [J]. BMJ, 2005, 331(7529): 1374.
12
Zuckerman JD. Hip fracture [J]. N Engl J Med, 1996, 334(23): 1519-1525.
13
Marottoli RA, Berkman LF, Cooney LMJ. Decline in physical function following hip fracture [J]. J Am Geriatr Soc, 1992, 40(9): 861-866.
14
Albini A, Malavasi VL, Vitolo M, et al. Long-term outcomes of postoperative atrial fibrillation following non cardiac surgery: A systematic review and metanalysis [J]. Eur J Intern Med, 2021, 85: 27-33.
15
Abdelgawad AME, Hussein MA, Naeim H, et al. A comparative study of TAVR versus SAVR in moderate and High-Risk surgical patients: hospital outcome and midterm results [J]. Heart Surg Forum, 2019, 22(5): E331-E339.
16
Almassi GH. Postoperative atrial fibrillation; the search goes on [J]. J Surg Res, 2015, 198(1): 57-58.
17
Danelich IM, Lose JM, Wright SS, et al. Practical management of postoperative atrial fibrillation after noncardiac surgery [J]. J Am Coll Surg, 2014, 219(4): 831-841.
18
Leibowitz D, Abitbol C, Alcalai R, et al. Perioperative atrial fibrillation is associated with increased one-year mortality in elderly patients after repair of hip fracture [J]. Int J Cardiol, 2017, 227: 58-60.
19
Tao L, Xiaodong X, Fan L, et al. Association between new-onset postoperative atrial fibrillation and 1-year mortality in elderly patients after hip arthroplasty [J]. Aging Clin Exp Res, 2020, 32(5): 921-924.
20
Varon B, Kandel L, Rivkin G, et al. New-Onset perioperative atrial fibrillation is associated with increased All-Cause mortality in elderly patients undergoing total knee and hip replacements [J]. Gerontology, 2021, 67(6): 681-686.
21
Dobrev D, Aguilar M, Heijman J, et al. Postoperative atrial fibrillation: mechanisms, manifestations and management [J]. Nat Rev Cardiol, 2019, 16(7): 417-436.
22
Mariscalco G, Engström KG. Atrial fibrillation after cardiac surgery: risk factors and their temporal relationship in prophylactic drug strategy decision [J]. Int J Cardiol, 2008, 129(3): 354-362.
23
Amar D, Zhang H, Miodownik S, et al. Competing autonomic mechanisms precede the onset of postoperative atrial fibrillation [J]. J Am Coll Cardiol, 2003, 42(7): 1262-1268.
24
Abu-Assi R, Campbell J, Bacchi S, et al. Association between atrial fibrillation and hip fractures and the implications for hip fracture patients: a systematic review [J]. ANZ J Surg, 2020, 90(4): 448-453.
25
Adunsky A, Arad M, Koren-Morag N, et al. Increased 1-year mortality rates among elderly hip fracture patients with atrial fibrillation [J]. Aging Clin Exp Res, 2012, 24(3): 233-238.
26
Khormaee S, Do HT, Mayr Y, et al. Risk of ischemic stroke after perioperative atrial fibrillation in total knee and hip arthroplasty patients [J]. J Arthroplasty, 2018, 33(9): 3016-3019.
27
Neuhaus V, King J, Hageman MG, et al. Charlson comorbidity indices and in-hospital deaths in patients with hip fractures [J]. Clin Orthop Relat Res, 2013, 471(5): 1712-1719.
28
van Dijk PAD, Bot AGJ, Neuhaus V, et al. Admission from nursing home residence increases acute mortality after hip fractures [J]. Geriatr Orthop Surg Rehabil, 2015, 6(3): 123-129.
29
Barceló M, Francia E, Romero C, et al. Hip fractures in the oldest old. Comparative study of centenarians and nonagenarians and mortality risk factors [J]. Injury, 2018, 49(12): 2198-2202.
30
Rostagno C, Cartei A, Rubbieri G, et al. Postoperative atrial fibrillation is related to a worse outcome in patients undergoing surgery for hip fracture [J]. Intern Emerg Med, 2021, 16(2): 333-338.
31
Sukhonthamarn K, Grosso MJ, Sherman MB, et al. Risk factors for unplanned admission to the intensive care unit after elective total joint arthroplasty [J]. J Arthroplasty, 2020, 35(7): 1937-1940.
32
Moon YJ, Kwon HM, Park YS, et al. Brief episodes of newly developed intraoperative atrial fibrillation predicts worse outcomes in adult liver transplantation [J]. Transplant Proc, 2018, 50(4): 1142-1146.
33
Kazaure HS, Roman SA, Tyler D, et al. The significance of atrial fibrillation in patients aged ≥ 55 years undergoing abdominal surgery [J]. World J Surg, 2015, 39(1): 113-120.
34
Frenkel Rutenberg T, Rutenberg R, Vitenberg M, et al. Prediction of readmissions in the first post-operative year following hip fracture surgery [J]. Eur J Trauma Emerg Surg, 2020, 46(5): 939-946.
35
Falk RH. Atrial fibrillation [J]. N Engl J Med, 2001, 344(14): 1067-1078.
36
van Diepen S, Bakal JA, McAlister FA, et al. Mortality and readmission of patients with heart failure, atrial fibrillation, or coronary artery disease undergoing noncardiac surgery: an analysis of 38 047 patients [J]. Circulation, 2011, 124(3): 289-296.
37
Lin MH, Kamel H, Singer DE, et al. Perioperative/postoperative atrial fibrillation and risk of subsequent stroke and/or mortality [J]. Stroke, 2019, 50(6): 1364-1371.
38
Chung MK, Martin DO, Sprecher D, et al. C-reactive protein elevation in patients with atrial arrhythmias: inflammatory mechanisms and persistence of atrial fibrillation [J]. Circulation, 2001, 104(24): 2886-2891.
39
Coumel P. Autonomic influences in atrial tachyarrhythmias [J]. J Cardiovasc Electrophysiol, 1996, 7(10): 999-1007.
40
Edwards JD, Wilkins RG. Atrial fibrillation precipitated by acute hypovolaemia [J]. Br Med J (Clin Res Ed), 1987, 294(6567): 283-284.
41
Walsh SR, Oates JE, Anderson JA, et al. Postoperative arrhythmias in colorectal surgical patients: incidence and clinical correlates [J]. Colorectal Dis, 2006, 8(3): 212-216.
42
Chelazzi C, Villa G, De Gaudio A R. Postoperative atrial fibrillation [J]. ISRN Cardiol, 2011, 2011: 203179.
43
Furuya K, Shimizu R, Hirabayashi Y, et al. Stress hormone responses to major intra-abdominal surgery during and immediately after sevoflurane-nitrous oxide anaesthesia in elderly patients [J]. Can J Anaesth, 1993, 40(5 Pt 1): 435-439.
44
Udelsman R, Goldstein DS, Loriaux DL, et al. Catecholamine-glucocorticoid interactions during surgical stress [J]. J Surg Res, 1987, 43(6): 539-545.
45
Heintz KM, Hollenberg SM. Perioperative cardiac issues: postoperative arrhythmias [J]. Surg Clin North Am, 2005, 85(6): 1103-1114, viii.
46
Christians KK, Wu B, Quebbeman EJ, et al. Postoperative atrial fibrillation in noncardiothoracic surgical patients [J]. Am J Surg, 2001, 182(6): 713-715.
47
Bajaj NS, Agarwal S, Rajamanickam A, et al. Impact of severe mitral regurgitation on postoperative outcomes after noncardiac surgery [J]. Am J Med, 2013, 126(6): 529-535.
48
Lai HC, Lai HC, Lee WL, et al. Mitral regurgitation complicates postoperative outcome of noncardiac surgery [J]. Am Heart J, 2007, 153(4): 712-717.
49
Bhave PD, Goldman LE, Vittinghoff E, et al. Incidence, predictors, and outcomes associated with postoperative atrial fibrillation after major noncardiac surgery [J]. Am Heart J, 2012, 164(6): 918-924.
50
Andrews TC, Reimold SC, Berlin JA, et al. Prevention of supraventricular arrhythmias after coronary artery bypass surgery. A meta-analysis of randomized control trials [J]. Circulation, 1991, 84(5 Suppl): III236-III244.
51
Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation: a major contributor to stroke in the elderly. The Framingham Study [J]. Arch Intern Med, 1987, 147(9): 1561-1564.
52
Kannel WB, Wolf PA, Benjamin EJ, et al. Prevalence, incidence, prognosis, and predisposing conditions for atrial fibrillation: population-based estimates [J]. Am J Cardiol, 1998, 82(8A): 2N-9N.
53
Stewart S, Hart CL, Hole DJ, et al. A population-based study of the long-term risks associated with atrial fibrillation: 20-year follow-up of the Renfrew/Paisley study [J]. Am J Med, 2002, 113(5): 359-364.
54
Gardin JM, Arnold AM, Bild DE, et al. Left ventricular diastolic filling in the elderly: the cardiovascular health study [J]. Am J Cardiol, 1998, 82(3): 345-351.
55
Benjamin EJ, Levy D, Anderson KM, et al. Determinants of doppler indexes of left ventricular diastolic function in normal subjects (the framingham heart study) [J]. Am J Cardiol, 1992, 70(4): 508-515.
56
Villareal RP, Hariharan R, Liu BC, et al. Postoperative atrial fibrillation and mortality after coronary artery bypass surgery [J]. J Am Coll Cardiol, 2004, 43(5): 742-748.
57
Xia VW, Worapot A, Huang S, et al. Postoperative atrial fibrillation in liver transplantation [J]. Am J Transplant, 2015, 15(3): 687-694.
58
La Manna G, Boriani G, Capelli I, et al. Incidence and predictors of postoperative atrial fibrillation in kidney transplant recipients [J]. Transplantation, 2013, 96(11): 981-986.
59
Sohn GH, Shin DH, Byun KM, et al. The incidence and predictors of postoperative atrial fibrillation after noncardiothoracic surgery [J]. Korean Circ J, 2009, 39(3): 100-104.
60
Kannel WB, Abbott RD, Savage DD, et al. Epidemiologic features of chronic atrial fibrillation: the Framingham study [J]. N Engl J Med, 1982, 306(17): 1018-1022.
61
Goette A, Kalman JM, Aguinaga L, et al. EHRA/HRS/APHRS/SOLAECE expert consensus on Atrial cardiomyopathies: Definition, characterisation, and clinical implication [J]. J Arrhythm, 2016, 32(4): 247-278.
62
Lau DH, Shipp NJ, Kelly DJ, et al. Atrial arrhythmia in ageing spontaneously hypertensive rats: unraveling the substrate in hypertension and ageing [J]. PLoS One, 2013, 8(8): e72416.
63
Verdecchia P, Angeli FB, Reboldi G. Hypertension and atrial fibrillation: doubts and certainties from basic and clinical studies [J]. Circ Res, 2018, 122(2): 352-368.
64
Bell DSH. Hypertension and diabetes: a toxic combination [J]. Endocr Pract, 2008, 14(8): 1031-1039.
65
Bell DSH. Diabetes: a cardiac condition manifesting as hyperglycemia [J]. Endocr Pract, 2008, 14(7): 924-932.
66
Turagam MK, Mirza M, Werner PH, et al. Circulating biomarkers predictive of postoperative atrial fibrillation [J]. Cardiol Rev, 2016, 24(2): 76-87.
67
Verdejo HE, Becerra E, Zalaquet R, et al. Atrial function assessed by speckle tracking echocardiography is a good predictor of postoperative atrial fibrillation in elderly patients [J]. Echocardiography, 2016, 33(2): 242-248.
68
Katsanos S, Mavrogenis AF, Kafkas N, et al. Cardiac biomarkers predict 1-Year mortality in elderly patients undergoing hip fracture surgery [J]. Orthopedics, 2017, 40(3): e417-e424.
69
Ausset S, Auroy Y, Lambert E, et al. Cardiac troponin I release after hip surgery correlates with poor long-term cardiac outcome [J]. Eur J Anaesthesiol, 2008, 25(2): 158-164.
70
Kim BS, Kim TH, Oh JH, et al. Association between preoperative high sensitive troponin I levels and cardiovascular events after hip fracture surgery in the elderly [J]. J Geriatr Cardiol, 2018, 15(3): 215-221.
71
Rader F, Van Wagoner DR, Ellinor PT, et al. Influence of race on atrial fibrillation after cardiac surgery [J]. Circ Arrhythm Electrophysiol, 2011, 4(5): 644-652.
72
Shen AYJ, Contreras R, Sobnosky S, et al. Racial/ethnic differences in the prevalence of atrial fibrillation among older adults--a cross-sectional study [J]. J Natl Med Assoc, 2010, 102(10): 906-913.
73
Alonso A, Agarwal SK, Soliman EZ, et al. Incidence of atrial fibrillation in whites and African-Americans: the Atherosclerosis Risk in Communities (ARIC) study [J]. Am Heart J, 2009, 158(1): 111-117.
74
Tokmaji G, McClure RS, Kaneko T, et al. Management strategies in cardiac surgery for postoperative atrial fibrillation: contemporary prophylaxis and futuristic anticoagulant possibilities [J]. Cardiol Res Pract, 2013, 2013: 637482.
75
Devereaux PJ, Yang H, Yusuf S, et al. Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial [J]. Lancet, 2008, 371(9627): 1839-1847.
76
Riber LP, Larsen TB, Christensen TD. Postoperative atrial fibrillation prophylaxis after lung surgery:systematic review and meta-analysis [J]. Ann Thorac Surg, 2014, 98(6): 1989-1997.
77
Goldman L. Supraventricular tachyarrhythmias in hospitalized adults after surgery. Clinical correlates in patients over 40 years of age after major noncardiac surgery [J]. Chest, 1978, 73(4): 450-454.
78
Kornej J, Börschel CS, Benjamin EJ, et al. Epidemiology of atrial fibrillation in the 21st century: novel methods and new insights [J]. Circ Res, 2020, 127(1): 4-20.
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