1 |
Risbud MV, Shapiro IM. Role of cytokines in intervertebral disc degeneration: pain and disc content [J]. Nat Rev Rheumatol 2014, 10(1): 44-56.
|
2 |
Ruiz-Fernández C, Francisco V, Pino J, et al. Molecular Relationships among Obesity, Inflammation and Intervertebral Disc Degeneration: Are Adipokines the Common Link? [J]. Int J Mol Sci, 2019, 20(8): 2030.
|
3 |
Walker BF. The prevalence of low back pain: a systematic review of the literature from 1966 to 1998 [J]. J Spinal Disord Tech, 2000, 13(3): 205-217.
|
4 |
Wang F, Cai F, Shi R, et al. Aging and age related stresses: a senescence mechanism of intervertebral disc degeneration [J]. Osteoarthr Cartilage, 2016, 24(3): 398-408.
|
5 |
Rider SM, Mizuno S, Kang JD. Molecular Mechanisms of Intervertebral Disc Degeneration [J]. Spine Surg Relat Res, 2018, 3(1): 1-11.
|
6 |
Le Maitre CL, Freemont AJ, Hoyland JA. The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration [J]. Arthritis Res Ther, 2005, 7(4): R732-R745.
|
7 |
Shamji MF, Setton LA, Jarvis W, et al. Proinflammatory cytokine expression profile in degenerated and herniated human intervertebral disc tissues [J]. Arthritis Rheum, 2010, 62(7): 1974-1982.
|
8 |
Feng C, Liu H, Yang M, et al. Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways [J]. Cell cycle, 2016, 15(13): 1674-1684.
|
9 |
Huang DW, Sherman BT, Lempicki RA. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists [J]. Nucleic Acids Res, 2009, 37(1): 1-13.
|
10 |
Bense RD, Sotiriou C, Piccart-Gebhart MJ, et al. Relevance of Tumor-Infiltrating Immune Cell Composition and Functionality for Disease Outcome in Breast Cancer [J]. J Natl Cancer Inst, 2016, 109(1): w192.
|
11 |
Newman AM, Liu CL, Green MR, et al. Robust enumeration of cell subsets from tissue expression profiles [J]. Nat methods, 2015, 12(5): 453-457.
|
12 |
Gentles AJ, Newman AM, Liu CL, et al. The prognostic landscape of genes and infiltrating immune cells across human cancers [J]. Nat Med, 2015, 21(8): 938-945.
|
13 |
Barrett T, Wilhite SE, Ledoux P, et al. NCBI GEO: archive for functional genomics data sets-update [J]. Nucleic acids research, 2013, 41(Database issue): D991-D995.
|
14 |
Davis S, Meltzer PS. GEOquery: a bridge between the Gene Expression Omnibus (GEO) and BioConductor [J]. Bioinformatics (Oxford, England), 2007, 23(14): 1846-1847.
|
15 |
Kazezian Z, Gawri R, Haglund L, et al. Gene Expression Profiling Identifies Interferon Signalling Molecules and IGFBP3 in Human Degenerative Annulus Fibrosus [J]. Sci Rep, 2015, 5:15662.
|
16 |
Thompson JP, Pearce RH, Schechter MT, et al. Preliminary evaluation of a scheme for grading the gross morphology of the human intervertebral disc [J]. Spine, 1990, 15(5): 411-415.
|
17 |
Gautier L, Cope L, Bolstad BM, et al. affy--analysis of Affymetrix GeneChip data at the probe level [J]. Bioinformatics, 2004, 20(3): 307-315.
|
18 |
Gentleman RC, Carey VJ, Bates DM, et al. Bioconductor: open software development for computational biology and bioinformatics [J]. Genome Biol, 2004,5(10): R80.
|
19 |
Ritchie ME, Phipson B, Wu D, et al. limma powers differential expression analyses for RNA-sequencing and microarray studies [J]. Nucleic Acids Res, 2015, 43(7): e47.
|
20 |
Szklarczyk D, Gable AL, Lyon D, et al. STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets [J]. Nucleic Acids Res, 2019, 47(D1): D607-D613.
|
21 |
Shannon P, Markiel A, Ozier O, et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks [J]. Genome Res, 2003,13(11): 2498-2504.
|
22 |
Chin CH, Chen SH, Wu HH, et al. cytoHubba: identifying hub objects and sub-networks from complex interactome [J]. BMC Syst Biol, 2014,8 Suppl 4: S11.
|
23 |
Chen B, Khodadoust MS, Liu CL, et al. Profiling Tumor Infiltrating Immune Cells with CIBERSORT [J]. Methods Mol Biol, 2018, 1711: 243-259.
|
24 |
Gu Z, Eils R, Schlesner M. Complex heatmaps reveal patterns and correlations in multidimensional genomic data [J]. Bioinformatics (Oxford, England), 2016, 32(18): 2847-2849.
|
25 |
Ginestet C. ggplot2: Elegant Graphics for Data Analysis [J]. J R Stat Soc Ser A Stat Soc, 2011, 174(1): 245.
|
26 |
Adai AT, Date SV, Wieland S, et al. LGL: Creating a map of protein function with an algorithm for visualizing very large biological networks [J]. J Mol Biol, 2004, 340(1): 179-190.
|
27 |
Urits I, Burshtein A, Sharma M, et al. Low Back Pain, a Comprehensive Review: Pathophysiology, Diagnosis, and Treatment [J]. Curr Pain Headache Rep, 2019, 23(3): 23.
|
28 |
Huang H, Cheng S, Zheng T, et al. Vitamin D retards intervertebral disc degeneration through inactivation of the NF-κB pathway in mice [J]. Am J Transl Res, 2019, 11(4): 2496-2506.
|
29 |
Endler P, Ekman P, Berglund I, et al. Long-term outcome of fusion for degenerative disc disease in the lumbar spine [J]. Bone Joint J, 2019, 101-B(12): 1526-1533.
|
30 |
Kaarniranta K, Kajdanek J, Morawiec J, et al. PGC-1α Protects RPE Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis [J]. Int J Mol Sci, 2018, 19(8): 2317.
|
31 |
Yang M, Peng Y, Liu W, et al. Sirtuin 2 expression suppresses oxidative stress and senescence of nucleus pulposus cells through inhibition of the p53/p21 pathway [J]. Biochem Biophys Res Commun, 2019, 513(3): 616-622.
|
32 |
Beierfuß A, Hunjadi M, Ritsch A, et al. APOE-knockout in rabbits causes loss of cells in nucleus pulposus and enhances the levels of inflammatory catabolic cytokines damaging the intervertebral disc matrix [J]. PloS one, 2019, 14(11): e225527.
|
33 |
Mattson DL. Immune mechanisms of salt-sensitive hypertension and renal end-organ damage [J]. Nat Rev Nephrol, 2019, 15(5): 290-300.
|
34 |
Richmond JM, Harris JE. Immunology and skin in health and disease [J]. Cold Spring Harb Perspect Med, 2014, 4(12): a15339.
|
35 |
Talmadge JE, Donkor M, Scholar E. Inflammatory cell infiltration of tumors: Jekyll or Hyde [J]. Cancer metastasis reviews, 2007, 26(3-4): 373-400.
URL
|
36 |
Sudo H, Yamada K, Iwasaki K, et al. Global identification of genes related to nutrient deficiency in intervertebral disc cells in an experimental nutrient deprivation model [J]. PloS one, 2013, 8(3): e58806.
|
37 |
Li Z, Shao Z, Chen S, et al. TIGAR impedes compression-induced intervertebral disc degeneration by suppressing nucleus pulposus cell apoptosis and autophagy [J]. J Cell Physiol, 2020, 235(2): 1780-1794.
|
38 |
Zhang Y, An HS, Thonar EJ A, et al. Comparative effects of bone morphogenetic proteins and sox9 overexpression on extracellular matrix metabolism of bovine nucleus pulposus cells [J]. Spine, 2006, 31(19): 2173-2179.
|
39 |
Wang Z, Weitzmann MN, Sangadala S, et al. Link protein N-terminal peptide binds to bone morphogenetic protein (BMP) type II receptor and drives matrix protein expression in rabbit intervertebral disc cells [J]. J Biol Chem, 2013, 288(39): 28243-28253.
|
40 |
Mallei A, Ieraci A, Corna S, et al. Global epigenetic analysis of BDNF Val66Met mice hippocampus reveals changes in dendrite and spine remodeling genes [J]. Hippocampus, 2018, 28(11): 783-795.
|
41 |
Chong MS, Goh LK, Lim WS, et al. Gene expression profiling of peripheral blood leukocytes shows consistent longitudinal downregulation of TOMM40 and upregulation of KIR2DL5A, PLOD1, and SLC2A8 among fast progressors in early Alzheimer's disease [J]. JJ Alzheimer's Dis: JAD, 2013, 34(2): 399-405.
|
42 |
Shi J, Gao S, Lv Z, et al. The association between rs12885713 polymorphism in CALM1 and risk of osteoarthritis: A meta-analysis of case-control studies [J]. Medicine, 2018, 97(36): e12235.
|
43 |
Chen P, Cao A, Miyagawa K, et al. Amphetamines promote mitochondrial dysfunction and DNA damage in pulmonary hypertension [J]. JCI insight, 2017, 2(2): e90427.
|
44 |
Yu AK, Datta S, McMackin MZ, et al. Rescue of cell death and inflammation of a mouse model of complex 1-mediated vision loss by repurposed drug molecules [J]. Hum mol genet, 2017, 26(24): 4929-4936.
|
45 |
Collins JC, Ghalei H, Doherty JR, et al. Ribosome biogenesis factor Ltv1 chaperones the assembly of the small subunit head [J]. J Cell Biol, 2018, 217(12): 4141-4154.
|
46 |
Pasaje CFA, Bae JS, Park B, et al. WDR46 is a Genetic Risk Factor for Aspirin-Exacerbated Respiratory Disease in a Korean Population [J]. Allergy Asthma Immunol Res, 2012, 4(4): 199-205.
|
47 |
Baek J, Lee J, Yun HS, et al. Kinesin light chain-4 depletion induces apoptosis of radioresistant cancer cells by mitochondrial dysfunction via calcium ion influx [J]. Cell Death Dis, 2018, 9(5): 496.
|
48 |
Bozza S, Käsermann F, Kaveri SV, et al. Intravenous immunoglobulin protects from experimental allergic bronchopulmonary aspergillosis via a sialylation-dependent mechanism [J]. Eur J Immunol, 2019, 49(1):195-198.
|
49 |
Giesbrecht K, Förmer S, Sähr A, et al. Streptococcal Pyrogenic Exotoxin A-Stimulated Monocytes Mediate Regulatory T-Cell Accumulation through PD-L1 and Kynurenine [J]. International journal of molecular sciences, 2019, 20(16): 3933.
|
50 |
Elsas P, Lee TH, Lenzi HL, et al. Monocytes activate eosinophils for enhanced helminthotoxicity and increased generation of leukotriene C4 [J]. Ann Inst Pasteur Immunol, 1987, 138(1): 97-116.
|
51 |
Gorth DJ, Shapiro IM, Risbud MV. Transgenic mice overexpressing human TNF-α experience early onset spontaneous intervertebral disc herniation in the absence of overt degeneration [J]. Cell Death Dis,2018, 10(1): 7.
|
52 |
Serr I, Fürst RW, Ott VB, et al. miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity [J]. Proc Natl Acad Sci U S A, 2016, 113(43): E6659-E6668.
|
53 |
Li Y, Luo W, Zhu S, et al. T Cells in Osteoarthritis: Alterations and Beyond [J]. Front Immunol, 2017, 8: 356.
|
54 |
Moriyama M, Nakamura S. Th1/Th2 Immune Balance and Other T Helper Subsets in IgG4-Related Disease [J]. Curr Top Microbiol Immunol, 2017, 401: 75-83.
|
55 |
Ali HR, Chlon L, Pharoah PDP, et al. Patterns of Immune Infiltration in Breast Cancer and Their Clinical Implications: A Gene-Expression-Based Retrospective Study [J]. PLoS Med, 2016, 13(12): e1002194.
|
56 |
Wehner JR, Fox-Talbot K, Halushka MK, et al. B cells and plasma cells in coronaries of chronically rejected cardiac transplants [J]. Transplantation, 2010, 89(9): 1141-1148.
|
57 |
Kim CJ, Romero R, Chaemsaithong P, et al. Chronic inflammation of the placenta: definition, classification, pathogenesis, and clinical significance [J]. Am J Obstet Gynecol, 2015, 213(4 Suppl): S53-S69.
|
58 |
Fristedt R, Borg D, Hedner C, et al. Prognostic impact of tumour-associated B cells and plasma cells in oesophageal and gastric adenocarcinoma [J]. J Gastrointest Oncol, 2016, 7(6): 848-859.
|
59 |
Grcević D, Kusec R, Kovacić N, et al. Bone morphogenetic proteins and receptors are over-expressed in bone-marrow cells of multiple myeloma patients and support myeloma cells by inducing ID genes [J]. Leuk Res, 2010, 34(6): 742-751.
|
60 |
Kaur HB, Lu J, Guedes LB, et al. TP53 missense mutation is associated with increased tumor-infiltrating T cells in primary prostate cancer [J]. Hum Pathol, 2019, 87: 95-102.
|