Abstract:

Osteoarthritis (OA) is a chronic inflammatory joint disease whose pathological changes are mainly degenerative changes of cartilage. The aggravation of social aging makes the incidence rate and disability rate of OA gradually rise, which has become one of the social problems puzzling human health. In recent years, there has been an increased interest in research on the correlation between metabolic abnormalities and OA, and many research results have emerged on the association between metabolic abnormalities and OA. The liver is the core organ of human metabolism, and a series of studies at home and abroad have shown that a large number of patients with OA have abnormal liver enzymology, which plays an important role in the occurrence and development of OA. In this paper, we focus on the role and mechanism of liver enzyme metabolism in the occurrence and development of OA and review the relevant literature.

Key words: Osteoarthritis, Liver enzyme, Metabolism