To analyze the independent risk factors of deep vein thrombosis (DVT) in the perioperative period of total knee arthroplasty in the elderly, and to explore D-dimer (D-Dimer), erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) for the predictive value of DVT.

A total of 160 elderly patients who underwent total knee arthroplasty in the Department of Orthopaedic Surgery of our hospital from January 2016 to July 2021 were retrospectively selected and divided into DVT group and no DVT group according to whether DVT occurred in the perioperative period. The independent risk factors of DVT were analyzed by univariate and logistic multivariate, and the receiver characteristic (ROC) curve was further drawn, and the critical value of ESR, CRP and D-Dimer for predicting DVT was determined according to the area under the curve (AUC).

The postoperative serum ESR, CRP and D-Dimer levels of the patients in the DVT group were significantly higher than those in the non-DVT group (P<0.05). Important risk factors for postoperative DVT in elderly patients (P<0.05); Logistic regression analysis found that age>80 years old, BMI>30kg/m2, postoperative bed rest time ≥5d, postoperative ESR, CRP and D-Dimer were independent risk factors for DVT (P<0.05). The ROC curve results showed that the AUCs of CRP, D-Dimer and ESR were 0.739, 0.893, and 0.725, respectively, which had good predictive value for DVT (P<0.05).

The occurrence of lower extremity DVT after knee arthroplasty in the elderly is closely related to age, BMI, operation time, postoperative bed rest time, postoperative serum ESR, CRP, D-Dimer levels, etc. The serum ESR, CRP, D-Dimer levels were detected after surgery The prediction effect of DVT is good, and it has certain clinical application value.