To investigate the effect of obliquely lateral lumbar interbody fusion (OLIF) on the recovery of lumbar function in patients with degenerative lumbar stenosis and its influence on the state of blood microcirculation and micro inflammation in the spinal canal.

120 patients with degenerative lumbar spinal stenosis admitted to the orthopedic inpatient department of Fengfeng Group General Hospital from January 2018 to January 2019 were selected for prospective study. The patients were randomly divided into observation group (with olif) and control group (with PLIF), with 60 cases in each group. The operation time, intraoperative blood loss, postoperative drainage volume, hospitalization time, visual analogue scale (VAS), Oswestry disability index (ODI), plasma viscosity (PV), high blood viscosity (HBV), low cut whole blood viscosity (LBV), erythrocyte sedimentation rate (ESR), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), hypersensitive C-reactive protein (hs-CRP), monocyte chemoattractant protein-1 (MCP-1) were compared between the two groups and clinical complications..

The operation time, intraoperative hemorrhage, postoperative drainage and hospitalization time in the observation group were all less than those in the control group (P<0.001); the total incidence of complications in the observation group (6.67%) was lower than that in the control group (21.67%, P<0.05); before treatment, there was no significant difference in the levels of vas, ODI, PV, HBV, LBV, ESR, hs CRP, IL-6, TNF-α and MCP-1 between the two groups (P>0.05); six months later The levels of VAS, ODI, PV, HBV,LBV, ESR, hs CRP, IL-6, TNF-α and MCP-1 in the two groups were all decreased (P<0.001). The levels of VAS, ODI, PV, HBV, LBV, ESR, hs CRP, IL-6, TNF-α and MCP-1 in the observation group were lower than those in the control group (P<0.001).

OLIF can significantly reduce the degree of postoperative lumbar pain in patients with degenerative lumbar stenosis, improve the lumbar function and blood microcirculation in the spinal canal, reduce the state of inflammation, and has significant clinical effect. Moreover, the operation time is short, the amount of intraoperative bleeding and postoperative drainage is small, the length of hospitalization is short, and the postoperative complications are small. It has the following advantages in the clinical treatment of degenerative lumbar stenosis. Important application value.