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Chinese Journal of Geriatric Orthopaedics and Rehabilitation(Electronic Edition) ›› 2020, Vol. 06 ›› Issue (01): 39-47. doi: 10.3877/cma.j.issn.2096-0263.2020.01.008

Special Issue:

• Spinal Disorders • Previous Articles     Next Articles

Establishment of clinical diagnosis system and evaluation of curative effect of brucellosis spondylitis in the elderly

Xinming Yang1,(), Ying Zhang1, Wei Shi1, Yao Yao1, Ye Tian1   

  1. 1. Department of Orthopedics, the First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, China
  • Received:2019-01-02 Online:2020-02-05 Published:2020-02-05
  • Contact: Xinming Yang

Abstract:

Objective

To establish the clinical diagnosis system of brucellosis spondylitis (BS) in the elderly and evaluate the treatment methods, so as to improve the diagnosis rate and cure rate of the disease.

Methods

Retrospective analysis of 70 elderly BS patients admitted to the first affiliated hospital of hebei northern university from January 2002 to December 2017. History, clinical, imaging, laboratory and pathology examinations were performed in accordance with the diagnostic system and it was confirmed as a confirmed case according to the diagnostic criteria. All patients were associated with varying degrees of cardiovascular and cerebrovascular disease, hypoproteinemia, moderate to severe malnutrition, osteoporosis and deep vein thrombosis. According to whether the operation was performed, the patients were divided into two groups: drug treatment group with 28 cases and drug+surgical treatment group with 42 cases. The two groups of patients evaluated the treatment methods according to VAS score, imaging score and clinical effect index. 3 months, 6 months and 12 months after treatment were selected as the main follow-up and evaluation points.

Results

All 70 patients were followed up for 6 to 12 months, with an average of 11.82±0.24 months. At the end of the follow-up, the complications of the two groups before treatment were effectively controlled. In drug+surgical treatment group, there was no recurrence, broken screw, broken rod or formation of sinus tract, intervertebral bone graft healing was good, and spinal stability was good. VAS scores were reduced in both groups.VAS scores in drug+surgical treatment group were 0 points at 3 months, 6 months and 12 months after treatment. The imaging scores of the two groups increased gradually, reaching 10 points at 6 months and 12 months after treatment in the drug + surgical treatment group. The clinical cure rate of the two groups increased gradually (P<0.05), and that of the drug+surgical treatment group reached 100% at 6 and 12 months after treatment.

Conclusions

For BS patients with non-surgical indications, the application of multidisciplinary collaboration and standardized drug therapy in the perioperative period can achieve good clinical efficacy. In line with surgical indications, the curative rate of surgical intervention can reach 100% and the curative effect is good.

Key words: Brucelliasis, Spondylitis, Standardization, Diagnosis, Clinical treatment

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